It is well known that good dental hygiene is essential for overall health and a higher standard of living. The oral cavity can help raise an early warning since it may be affected by systemic illness and be the source of its symptoms. Using an online survey tool, this longitudinal survey was conducted among dentists and dental students in Riyadh. Participants were approached by Riyadh's dental clinics, hospitals, and institutions, and asked to complete the survey. A total of 381 responses were obtained from the participants, including 28% general practitioners, 72% students/interns, 66% females, and 34% males. Given that most p-values are less than 0.05, the general practitioners exhibit noticeably greater levels of knowledge than the students/intern group. The participants' general level of awareness and knowledge was below average. Students must be taught about the association between uncommon systemic illnesses in children and how they affect their oral health.