Maxillofacial space infections are one of the most common types of head and neck infections, which are of great importance in terms of both aesthetics and proximity to sensitive areas of the body. This study aimed to investigate the etiology and epidemiology of maxillofacial space infections in patients referred to the maxillofacial surgery department. During this cross-sectional study, the medical records of patients who had been referred to the hospital due to jaw abscess were reviewed. The items studied included gender, age, tooth causing the infection, type of abscess, symptoms of the disease, systemic problems, smoking and alcohol consumption, type of antibiotic prescribed, type of anesthesia, surgical method, length of hospitalization, and postoperative complications. SPSS V23 software was used in data analysis. In this study, 209 people, including 86 women (41.1%) and 123 men (58.9%), with a mean age of 35.45 ± 14.19 years, participated. The most frequent cause of infection was the lower third molar with 56 cases (26.8%), the most common infected space was the submandibular with 108 cases (51.7%), and the most frequent symptoms of abscesses were swelling with 179 cases (85.6%). The most common complication was Ludwig's angina, and the most frequent antibiotic prescribed was clindamycin in 151 cases. According to the results of this study, maxillofacial abscesses can cause irreversible complications for patients. Patients whose pterygomandibular and submandibular spaces were infected were hospitalized for a longer period compared to others.
