The objective of this research was to analyze the spatial correlation between the incisive canal (IC) and the periapical zone of maxillary central incisors in a Korean population, using cone-beam computed tomography (CBCT). The data acquired are meant to refine and support the strategizing and performance of immediate implant insertion in the maxillary aesthetic region. Imaging data were collected from 94 subjects (48 male, 46 female) aged 20–79 years at a dental facility in Seoul, South Korea. Participants were stratified into three age brackets: 20–39 years, 40–59 years, and 60–79 years. Grounds for exclusion encompassed absent maxillary anterior teeth, notable dental crowding, periodontal disease, pathological conditions, and scan distortions. Dimensions from the root tip to the incisive canal (RIC-11-P, RIC-21-P) and from the root tip to the labial bone plate (RBB-11-B, RBB-21-B) were captured from the CBCT scans. Statistical testing employed Welch’s t-test, analysis of variance, and Pearson’s correlation, adopting a significance threshold of P < 0.05. Average separations between the root apex and the incisive canal came to 3.77 mm (RIC-11-P) and 3.62 mm (RIC-21-P), whereas mean labial bone distances were 0.86 mm and 0.94 mm, respectively. Men consistently registered markedly larger spans than women across both NPC-to-apex and labial bone metrics. Age-associated shifts were observed, with younger cohorts showing shorter distances from the IC to the root tip. Still, the ANOVA and Pearson correlation outputs failed to establish a significant statistical relationship among these measurements across the various age tiers. The investigation highlights pronounced sex-based differences in central incisor anatomy, with males exhibiting longer spans from the apex to both the IC and the labial bone, a finding relevant to surgical insertion. Although age-dependent trends emerged, they had little effect on average distances. These observations stress the imperative for individualized therapeutic design in immediate implant procedures, with particular attention directed toward sex and age. Cross-referencing with other ethnic studies suggests that such morphological traits may be stable across diverse populations, though idiosyncratic variability must continue to be weighed.
