This study conducts a systematic review of the literature in this field, focusing on the use of antibiotics and antiseptic agents in oral health research. Specifically, it examines the effectiveness of using amoxicillin, amoxiclav, and chlorhexidine as prophylactic treatments following tooth extraction. The research began with a thorough search of relevant studies in various medical databases such as Google Scholar, Medline, PubMed, and other trusted online sources. Both the methodologies and outcomes of the identified studies were assessed. A filtering process was applied to select the most pertinent and reliable articles, resulting in the inclusion of 1,750 articles. These studies were assessed against specific eligibility criteria to exclude irrelevant studies. Ultimately, 10 studies, primarily randomized control trials (RCTs) and clinical trials were selected for this review. These studies directly focused on the use of amoxicillin, amoxiclav, and chlorhexidine as prophylactic agents to prevent oral infections after tooth extractions. The review found that amoxicillin and chlorhexidine were the most commonly used prophylactics, with amoxicillin being particularly effective in reducing complications following tooth extraction. Although chlorhexidine was less effective than antibiotics, it remains an easy and low-risk addition to the procedure.
