Written by Georgiy Khetagovich Kibizov
Published on Vol 6 , 2026
This study aimed to comprehensively assess the impact of type 1 diabetes mellitus (T1DM) on the periodontal status of adolescents. A cross-sectional comparative study involved 180 adolescents aged 12–18 years, divided into groups: patients with compensated T1DM (n=80), conditionally healthy individuals (n=80), and adolescents with periodontitis associated with poor oral hygiene (n=20). The methodology included clinical assessment of periodontal indices (BOP, PPD, CAL), quantitative determination
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Written by Nur-Mukhammad Ayubovich Musaev
Published on Vol 6 , 2026
This single-center cross-sectional study aimed to assess the prevalence and structure of cardiometabolic disorders in patients with chronic periodontitis in real-world clinical practice. A cohort of 212 patients (mean age 51.3±8.7 years) from a dental clinic with a verified diagnosis of moderate or severe periodontitis was included. All participants, in addition to dental examination with determination of CPI, PPD, and CAL indices, underwent comprehensive therapeutic and laboratory examination,
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Repeated bonding of orthodontic brackets is a common clinical necessity, yet its impact on shear bond strength (SBS) and enamel integrity remains inadequately characterized. This study evaluated the effect of multiple bonding cycles using the same bracket on SBS and enamel surface characteristics. Twenty human premolars extracted for orthodontic purposes were randomly allocated to two groups (n=10 per group): Group A (Enlight® adhesive, Ormco) and Group B (Transbond XT® adhesive, 3M Unitek). Spe
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Written by Mata Soslanbekovna Mustapaeva
Published on Vol 6 , 2026
The high prevalence of early childhood caries, reaching 80-100% in some regions, highlights the need for safe, convenient products for long-term home remineralization therapy. Existing methods are limited by short enamel contact time, frequent dental visits, and risks associated with high fluoride concentrations in children. This study conducted a preclinical evaluation of the safety and efficacy of an innovative complex for remineralization therapy of initial caries in children. The complex con
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Written by Inal Andzorovich Vorokov
Published on Vol 6 , 2026
This study evaluates the importance and effectiveness of the timely treatment of distal occlusion. The study involved 220 individuals aged 23 to 40 years, divided into four groups: 60 patients who underwent orthodontic treatment for distal occlusion before age 18; 60 patients treated at age 25-32 years; 60 untreated patients with distal occlusion; and 40 individuals with physiological occlusion as controls. All participants underwent a comprehensive examination, including cephalometric analysis,
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Written by Kamila Alibekovna Saypulaeva
Published on Vol 6 , 2026
Oral squamous cell carcinoma remains a pressing issue due to high incidence, late diagnosis, and limited effectiveness of standard treatments with severe toxic effects. This study compared the antitumor activity and safety of Curcuma longa, Camellia sinensis, and Nigella sativa extracts in a rat model of DMBA-induced oral cancer. The experiment involved 78 adult male Wistar rats. Acute toxicity was assessed at 5000 mg/kg. Tumors were induced by applying 0.5% DMBA to the buccal mucosa three times
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