The objective of this study was to evaluate the influence of oral health on Oral Health Related Quality of Life (OHRQoL) in individuals who sought oral health management at the Periodontology Department, Oral Pathology, and Dental Prophylaxis at the Dental Clinic (UDC) University in Kraków. This cross-sectional study, involving 250 adult patients, incorporated both intraoral clinical examinations and questionnaire-based surveys. A statistically significant negative relationship was observed between the self-assessment of OHRQoL and OHIP-14 concerning teeth, oral mucosa, and dentures. Compared to patients who did not report caries concerns, those who did had a poorer OHRQoL. Reports of OHRQoL self-evaluations were lower among those who wanted prosthetic therapy than among those who did not. Patients referring the clinic for follow-up visits had a better self-assessment of OHRQoL compared to those seeking management. OHRQoL demonstrated a negative and statistically significant association with these factors: 1) DMFT index, 2) count of decayed teeth, and 3) count of missing teeth. Dental health care providers should maintain the prevention of tooth decay as their main objective so that patients can retain as many healthy teeth as possible. It seems that the effect of regular dental visits on patients’ well-being is less significant.