The study aimed to compare the effectiveness of four commercially available remineralizing products: GC Tooth Mousse, SHY-NM, Biomed Calcimax, and Bentodent, on demineralized human teeth. A total of 72 upper premolars, each bonded with a 3M premolar bracket, were randomly assigned to one of six groups, each containing 12 teeth. Group 1 was stored in de-ionized water (positive control), group 2 in Tencates demineralizing solution (negative control), group 3 in Tencates solution and coated with GC Tooth Mousse every 4 hours, group 4 was coated with SHY-NM, group 5 was coated with Biomed Calcimax, and group 6 was coated with Bentodent. After 96 hours, the teeth were sectioned using a diamond disc and thinned to 150-200 µm with a carborundum stone. The segments were examined under a polarized light microscope, and the images were analyzed using ImageJ software. A Bonferroni post-hoc test for multiple pairwise comparisons showed significant differences in the depth of demineralization between most groups, except between group 3 and group 4, as well as group 5 and group 4 for minimum demineralization depth. For maximum demineralization depth, significant differences were observed between group 2 and group 6, group 3 and group 4, group 4 and group 5, and group 5 and group 6. The results indicate that GC Tooth Mousse and SHY-NM are more effective in remineralizing artificially induced carious lesions compared to Biomed Calcimax and Bentodent.
