The integration of orthodontic and periodontal care represents a critical interdisciplinary approach to managing complex dental conditions, where patient-reported outcomes (PROs) serve as essential indicators of treatment success beyond clinical metrics. This narrative review synthesizes evidence from peer-reviewed literature published on PROs in orthodontic–periodontal interdisciplinary care. Key themes include pain, discomfort, oral health-related quality of life (OHRQoL), treatment satisfaction, functional impairments, and periodontal health perceptions. The review highlights studies on combined therapies for conditions such as palatally impacted canines, stage IV periodontitis, tilted molars, intra-bony defects, and retention phases, emphasizing how interdisciplinary interventions influence patient experiences. For instance, accelerated orthodontic methods for impacted canines show variable impacts on treatment time and PROs, while alveolar ridge preservation post-extraction improves patient satisfaction alongside bone maintenance. Combined periodontal-orthodontic treatments for severely compromised teeth demonstrate high patient acceptance despite advanced disease, with low pain levels and improved self-perceived outcomes. Retention strategies, including CAD/CAM-based retainers, reveal favorable PROs related to stability and periodontal health. Mobile applications and social media interventions enhance behavioral changes, positively affecting PROs during orthodontic care with periodontal considerations. Overall, the findings underscore the value of PROs in optimizing interdisciplinary protocols, revealing gaps in long-term data and the need for standardized measures. This review aims to guide clinicians in incorporating patient perspectives to enhance care quality and outcomes in orthodontic–periodontal collaborations.
