Odontogenic inflammatory illnesses, which make up 26% of all inflammatory diseases, have remained the most common type of proinflammatory disorders of the maxillofacial region (MFO) in Russia throughout the past few decades. Phlegmons and abscesses can cause a lot of serious problems, so the diagnosis and treatment of these diseases remain important issues. The study aimed to develop new strategies for the treatment of inflammatory diseases using phyto-adaptogenic, and the results showed that animals receiving classical antibacterial therapy in addition to an adaptogen experienced a significant decrease in the qualitative and quantitative composition of microflora and an improvement in clinical symptoms in the early stages. Thus, the use of adaptogens in the treatment of inflammatory illnesses is recommended. Therefore, the use of adaptogens in the treatment of inflammatory diseases of the maxillofacial region is beneficial because has been shown that they must be significant moderators of the body's reaction.