A contemporary and rapidly developing field for the treatment of a wide range of diseases and ailments is photodynamic therapy. Cytotoxic reactive oxygen species are produced because of a light-mediated photochemical process that activates photosensitizing substances. It is used to treat a variety of oral potentially malignant disorders (OPMDs) as well as periodontal and peri-implant diseases by providing light-activated microbial killing. Photodynamic therapy is a non-invasive, non-toxic, and repeatable procedure that causes no collateral damage. Photodynamic therapy was performed using a low-level diode laser (660 nm at 50 mW) and a photosensitizing dye (1% methylene blue) for one minute. PDT was successful in improving the clinical parameters of cases of periodontitis and peri-implantitis, as well as the overall clinical improvement of symptoms in oral lichen planus cases. These three modalities—management of periodontitis, peri-implantitis, and oral lichen planus—are highlighted in this case series. Therefore, the potential of PDT as a therapy adjunct has been demonstrated.
