TY  - JOUR
T1  - Clinical and Laboratory Characteristics of Periodontal Disease in Adolescents with Type 1 Diabetes
A1  - Georgiy Khetagovich Kibizov
A1  - Yana Makharbekovna Bedoeva
A1  - Angelina Zoltanovna Kazieva
A1  - Lana Rafikovna Makieva
A1  - Irina Aleksandrovna Tokaeva
A1  - Diana Olegovna Gudieva
A1  - Iman Alamovna Muzaeva
A1  - Alexandr Elkanovich Kharebov
A1  - Anastasia Igorevna Shmailova
A1  - Maryam Muradovna Alangerieva
JF  - Asian Journal of Periodontics and Orthodontics
JO  - Asian J Periodontics Orthod
SN  - 3062-3499
Y1  - 2026
VL  - 6
IS  - 1
DO  - 10.51847/EgocWZMp5C
SP  - 1
EP  - 12
N2  - This study aimed to comprehensively assess the impact of type 1 diabetes mellitus (T1DM) on the periodontal status of adolescents. A cross-sectional comparative study involved 180 adolescents aged 12–18 years, divided into groups: patients with compensated T1DM (n=80), conditionally healthy individuals (n=80), and adolescents with periodontitis associated with poor oral hygiene (n=20). The methodology included clinical assessment of periodontal indices (BOP, PPD, CAL), quantitative determination of key periodontopathogenic bacteria (Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola) using real-time PCR, and analysis of biochemical markers (interleukin-1β, matrix metalloproteinase-8, osteoprotegerin) in oral fluid. The results revealed that adolescents with T1DM, compared to their healthy peers, had a 2.5 times higher bleeding index (BOP: 25.0% vs. 10.5%, p
UR  - https://tsdp.net/article/clinical-and-laboratory-characteristics-of-periodontal-disease-in-adolescents-with-type-1-diabetes-j7y0o7diwuanoqt
ER  -