%0 Journal Article
%T Clinical and Laboratory Characteristics of Periodontal Disease in Adolescents with Type 1 Diabetes
%A Georgiy Khetagovich Kibizov
%A Yana Makharbekovna Bedoeva
%A Angelina Zoltanovna Kazieva
%A Lana Rafikovna Makieva
%A Irina Aleksandrovna Tokaeva
%A Diana Olegovna Gudieva
%A Iman Alamovna Muzaeva
%A Alexandr Elkanovich Kharebov
%A Anastasia Igorevna Shmailova
%A Maryam Muradovna Alangerieva
%J Asian Journal of Periodontics and Orthodontics
%@ 3062-3499
%D 2026
%V 6
%N 1
%R 10.51847/EgocWZMp5C
%P 1-12
%X This study aimed to comprehensively assess the impact of type 1 diabetes mellitus (T1DM) on the periodontal status of adolescents. A cross-sectional comparative study involved 180 adolescents aged 12–18 years, divided into groups: patients with compensated T1DM (n=80), conditionally healthy individuals (n=80), and adolescents with periodontitis associated with poor oral hygiene (n=20). The methodology included clinical assessment of periodontal indices (BOP, PPD, CAL), quantitative determination of key periodontopathogenic bacteria (Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola) using real-time PCR, and analysis of biochemical markers (interleukin-1β, matrix metalloproteinase-8, osteoprotegerin) in oral fluid. The results revealed that adolescents with T1DM, compared to their healthy peers, had a 2.5 times higher bleeding index (BOP: 25.0% vs. 10.5%, p
%U https://tsdp.net/article/clinical-and-laboratory-characteristics-of-periodontal-disease-in-adolescents-with-type-1-diabetes-j7y0o7diwuanoqt