TY - JOUR T1 - An In-Silico Evaluation of Force Transmission Pathways in Teeth with Heterogeneous Periodontal Attachment Loss A1 - Ahmed S. Hassan A1 - Omar K. Youssef A1 - Mariam A. Fathy A1 - Karim M. Abdelrahman A1 - Nour A. Saleh JF - Asian Journal of Periodontics and Orthodontics JO - Asian J Periodontics Orthod SN - 3062-3499 Y1 - 2024 VL - 4 IS - 1 DO - 10.51847/ZDrdZpPtBy SP - 246 EP - 254 N2 - The periodontal ligament (PDL) serves as a critical interface for force transmission between teeth and alveolar bone, modulating biomechanical responses during occlusal loading and orthodontic interventions. Heterogeneous periodontal attachment loss, characteristic of advanced periodontitis, disrupts this equilibrium, potentially altering force pathways and exacerbating tissue strain. This conceptual manuscript proposes a novel theoretical framework—the Differential Force Cascade Model (DFCM)—to elucidate how uneven attachment loss influences force propagation in teeth. Drawing on biomechanical principles, the DFCM posits that regions of reduced attachment redirect forces through compensatory pathways, leading to localized stress amplification and altered load distribution. The framework integrates concepts from recent literature on PDL biomechanics and in-silico modeling, emphasizing non-uniform tissue responses without empirical data. By conceptualizing force transmission as a networked cascade influenced by attachment heterogeneity, the DFCM offers a foundation for future in-silico evaluations, potentially informing theoretical advancements in orthodontics and periodontics. This approach highlights the need for nuanced models that account for spatial variability in periodontal integrity, fostering deeper understanding of mechanobiological dynamics in compromised dentition. The manuscript synthesizes key theoretical insights from publications, advocating for refined conceptual paradigms in dental biomechanics. UR - https://tsdp.net/article/an-in-silico-evaluation-of-force-transmission-pathways-in-teeth-with-heterogeneous-periodontal-attac-yuxz3krh63aqtre ER -