A significant percentage of the general population suffers from a wide range of conditions called temporomandibular joint (TMJ) disorders. Orofacial pain that intensifies with jaw movement is its defining feature. The diagnosis is strictly clinical. NSAIDs and self-care have played a major role in the treatment of this condition. Furthermore, since the condition is musculoskeletal in origin, botulinum injection has been suggested as a potential treatment option. Our goal was to examine the literature on the epidemiology, clinical presentation, diagnosis, and treatment of TMJ problems. In addition, we investigated recent research demonstrating the effectiveness of Botox injections in the treatment of this condition. The selection of publications was done using the PubMed database, and papers were acquired and examined. High morbidity is associated with TMD. Therefore, whenever clinicians encounter this condition, appropriate management is essential. The cornerstone of treatment for this condition has been self-care practices combined with NSAIDs for pain management. For chronic cases, Botox injections and muscle relaxants are other alternatives. However, most published studies on the effectiveness of Botox have produced conflicting results, as pain is subjective. More research is needed before Botox can be considered a first-line treatment.
