%0 Journal Article
%T A Conceptual Risk-Stratification Framework for Orthodontic Treatment in Periodontal Patients
%A Hiroshi Tanaka
%A Lukas M. Fischer
%A Tesfaye M. Bekele
%J Asian Journal of Periodontics and Orthodontics
%@ 3062-3499
%D 2025
%V 5
%N 1
%R 10.51847/CCnk1WTTeG
%P 225-235
%X Orthodontic treatment in patients with existing or treated periodontal disease poses unique challenges due to the interplay of biological vulnerabilities, biomechanical stresses, and behavioral factors that can exacerbate periodontal breakdown or compromise treatment outcomes. This conceptual manuscript proposes an original multi-level risk-stratification framework to guide interdisciplinary treatment planning. Drawing from periodontal pathophysiology, bone remodeling biology, orthodontic force-response theory, and clinical risk assessment principles, the framework integrates key constructs including periodontal inflammatory status, alveolar bone support and defect morphology, periodontal phenotype, orthodontic force magnitude and biomechanics, plaque control and patient adherence, and systemic risk modifiers such as smoking and diabetes. Risk is stratified across low, moderate, and high categories based on a synthesized evaluation of biological, biomechanical, and behavioral domains, facilitating tailored orthodontic strategies that prioritize periodontal stability and long-term occlusal function. The model emphasizes pre-orthodontic periodontal optimization, customized biomechanics to minimize iatrogenic damage, and ongoing monitoring of patient compliance. By providing a biologically informed decision-making tool, this framework addresses unmet needs in clinical practice, potentially reducing adverse events like further bone loss, tooth mobility, or relapse. It underscores the necessity for collaboration between periodontists and orthodontists to enhance treatment predictability in this high-risk population. Future empirical validation could refine its application in diverse clinical settings. 
%U https://tsdp.net/article/a-conceptual-risk-stratification-framework-for-orthodontic-treatment-in-periodontal-patients-ztffiytwymbtqql