This umbrella review investigates whether periodontal disease in expectant mothers is linked to an increased likelihood of preterm birth and infants with low birth weight. A thorough search of biomedical literature was performed up to November 2021 using PubMed/Medline, Cochrane Library, Scopus, EMBASE, Web of Science, Scielo, LILACS, and Google Scholar. Included studies were systematic reviews in English, with no restriction on publication date, that examined the relationship between maternal periodontal health and adverse birth outcomes. The methodological rigor of the studies was evaluated using AMSTAR-2, and the certainty of evidence along with recommendation strength was assessed through GRADEPro GDT. From 161 initially identified articles, 15 met the inclusion criteria, and seven were suitable for meta-analysis. Findings indicate a notable association between periodontal disease during pregnancy and elevated risks of both preterm delivery and low birth weight in newborns. Maternal periodontal disease appears to be associated with higher chances of preterm birth and low birth weight, highlighting the importance of oral health management during pregnancy.
